Cellular therapy in Tuberculosis

Evaluation of Cellular Immune Response against Purified Antigen 85 in Patients with Tuberculosis

Background: Tuberculosis (TB) remains an important health problem throughout the world. Despite its significance in public health, mechanisms of protective immunity against Mycobacyerium Tuberculosis in humans have not yet been understood. Objective: To evaluate cell mediated immune response against purified Ag 85, PPD and Phytohemagglutinin (PHA) in patients with tuberculosis and healthy tuber...

Streptomycin Therapy in Tuberculosis

The following is a report on the effect of streptomycin in twenty-one suitable cases of tuberculosis treated in the Hardinge Hospital (Dharampore and Arcadia Dharampore) during the year 1948. Clinical material.?All patients in this series had pulmonary tuberculosis which, prior to streptomycin therapy, had not responded to bedrest or other accepted forms, of treatment. There was roentgenographi...

Improved efficiency in detecting cellular immunity towards M. tuberculosis in patients receiving immunosuppressive drug therapy.

BACKGROUND Reactivation of a latent Mycobacterium tuberculosis infection in immunocompromised individuals is associated with significant morbidity and mortality. The limited sensitivity of the established tuberculin skin-test in identifying latently infected patients on immunosuppressive drug therapy represents a major obstacle to better tuberculosis control after transplantation. METHODS In ...

I. K. Therapy in Tuberculosis

Cyanacethydrazide therapy in pulmonary tuberculosis.

The efficacy of isoniazid in the treatment of pulmonary tuberculosis stimulated the search for related drugs that might increase the effectiveness of antituberculosis therapy especially in those chronically ill patients in whom INH does not produce the desired effect or who are unable to tolerate it. Such a compound is cyanacethydrazide** which as its formula indicates is structurally related t...